How Preimplantation Genetic Testing (PGT) Improves IVF Success Rates

For those who are struggling with infertility and undergoing IVF treatments, the dream of parenthood may seem far away. Despite many trials, when IVF continues to fail, couples start to wonder – What more can we do? Well, there is some good news! There is still hope. Have you heard of Preimplantation Genetic Testing, or PGT? This powerful tool is helping couples just like you, who have faced repeated IVF failures, take one step closer to achieve their dream of a healthy pregnancy.

But before we deep dive into PGT, let’s quickly understand the basics of IVF and how the two work together.

What Is IVF?

IVF refers to In-Vitro Fertilisation. It is a fertility treatment where eggs are retrieved from a woman’s ovaries and fertilised with sperm outside her body (i.e. in a laboratory). The resulting embryos are then closely monitored, and one or more are transferred to the uterus with the hope of achieving pregnancy. 1 2

What Is Preimplantation Genetic Testing?

Preimplantation Genetic Testing is a medical procedure performed during IVF (In Vitro Fertilisation) that screens embryos for genetic abnormalities before they are transferred to the uterus. By analysing just a few cells from the embryo (without harming its development), PGT helps fertility specialists identify the healthiest embryos for transfer. 3 4

Why is PGT Important in IVF?

PGT improves the success rate of IVF procedures because even with IVF, many pregnancies fail due to hidden genetic issues in embryos. This laboratory technique helps in several ways. Let us have a look at them. 3

Key Benefits: 3 5

  • It ensures that the embryo selected for transfer has the correct number of chromosomes.
  • This reduces the chances of a failed IVF cycle or miscarriage.
  • It also examines embryos for a range of genetic problems that can cause implantation failure, miscarriage and birth defects in a resulting child. 5
  • With better and timely embryo selection, couples may achieve success in fewer cycles, saving time, cost, and emotional stress.
  • PGT reduces the risk of genetic conditions being passed on to the child.

Types of Preimplantation Genetic Testing

It is classified into 3 types, each designed to address specific concerns: 4

  • PGT-A (for Aneuploidy): Detects abnormal chromosome numbers, often responsible for failed IVF cycles. 6
  • PGT-M (for Monogenic Disorders): Screens for inherited single-gene disorders such as cystic fibrosis or thalassemia. 6 7
  • PGT-SR (for Structural Rearrangements): Identifies embryos with missing or rearranged chromosome segments. 5

Who Should Consider PGT?

Preimplantation Genetic testing is especially recommended for: 3 4 5

  • Couples with repeated IVF failures or miscarriages.
  • Women over 37, where chromosomal issues are more common.
  • Couples who have a family history of genetic disorders.
  • Anyone wanting to reduce the risk of passing on inherited conditions.

Why Choose LifeCell Diagnostics for PGT?

LifeCell Diagnostics offers comprehensive Preimplantation Genetic Testing to give couples the highest chance of success in their IVF journey. With cutting-edge genetic testing platforms and expert genetic counsellors, they ensure:

  • Accurate embryo screening for improved IVF outcomes
  • Comprehensive testing for chromosomal and monogenic disorders
  • Analyses 96 samples in just one go
  • 3-hour sample preparation time
  • Trusted expertise, backed by India’s leading brand in genetic and stem cell sciences

This way, couples struggling with infertility can approach IVF with greater confidence, knowing their chances of a healthy pregnancy have significantly improved.

Final Thoughts

IVF is already a remarkable advancement in reproductive medicine, but when combined with Preimplantation Genetic Testing, the success rates reach new heights. For couples who have faced repeated setbacks, PGT offers hope, reassurance, and also shows the path towards a healthier pregnancy. With LifeCell Diagnostics by your side, that dream is closer than ever.

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